Which condition is associated with a lack of pancreatic hormone?

Diabetes mellitus is a condition that is directly associated with a lack of insulin, which is a crucial hormone produced by the pancreas. In individuals with diabetes, either the pancreas does not produce enough insulin (Type 1 diabetes) or the body cannot effectively use the insulin produced (Type 2 diabetes). Insulin is vital for regulating blood glucose levels, and its deficiency leads to elevated blood sugar levels characteristic of diabetes mellitus. Therefore, the association between a lack of pancreatic hormone, specifically insulin, and diabetes makes this the correct answer.

The other conditions listed do not involve a direct deficiency of pancreatic hormones. Hypoglycemia refers to low blood sugar, which might result from excessive insulin but is not a lack of pancreatic hormone itself. Hyperthyroidism and hypothyroidism are conditions related to the thyroid gland's overproduction or underproduction of thyroid hormones, respectively, and are not connected to pancreatic hormone levels.